Parameters

Non-defeated mice

30 days of SDS mice

Vehicle-control mice

Ladasten 30 mg/kg, i.p.

Vehicle

Ladasten, 30 mg/kg, i.p.

Latency to the first immobility, s

74.6 ± 7.8

75.7 ± 8.4

41.6 ± 8.4^*

57.1 ± 15.7

Immobility time, s

201.1 ± 9.3

191.4 ± 9.9

245.7 ± 9.9^*

204.1 ± 15.6^#

Thymic index, mg/10g body weigh

24.4 ± 1.4

22.8 ± 1.7

14.8 ± 2.2^*

19.8 ± 1.5^#

Spleen index, mg/10g body weigh

31.1 (29.1/33.5)

36.8 (35.7/39.6)

62.5^$$ (38.3/75.3)

51.3^$ (38.2/55.9)